Grant Decoding Neurodegeneration
Investigating Distinct and Overlapping Mechanisms in TDP-43 Proteinopathies
Summary:
This R01 research grant, funded by the National Institutes of Health (NIH), seeks to investigate the underlying mechanisms behind various neurodegenerative diseases associated with the abnormal accumulation of the protein TDP-43. These diseases, collectively known as TDP-43 proteinopathies, include:
- Limbic-predominant age-related TDP-43 encephalopathy (LATE)
- Frontotemporal dementia (FTD)
- Amyotrophic lateral sclerosis (ALS)
- Other atypical dementia and related disorders (ADRDs)
The project aims to identify both distinct and overlapping mechanisms contributing to the development and progression of these diverse pathologies. By understanding these mechanisms, researchers hope to develop more targeted therapies and interventions for these currently incurable diseases.
Sponsor:
National Institutes of Health (NIH)
Eligibility:
The grant is open to researchers affiliated with U.S. institutions, including:
- Universities and colleges
- Medical schools and research institutions
- Non-profit organizations
Benefits:
- Funding to support research costs for a period of up to 5 years
- Opportunity to contribute to groundbreaking research on TDP-43 proteinopathies
- Collaboration with leading experts in the field
- Potential for significant advancements in the understanding and treatment of these diseases
Deadline:
Oct 04, 2024.
